Trevor Leong, radiation-oncologist, Peter MacCallum Cancer Centre, Melbourne, Australia

Biography

Professor Trevor Leong is a consultant Radiation Oncologist and past Director of Radiation Oncology at Peter MacCallum Cancer Centre, Melbourne. He holds senior leadership positions with oncology organisations including the Australasian Gastro-Intestinal Trials Group (AGITG), the Trans-Tasman Radiation Oncology Group (TROG), the European Society for Medical Oncology (ESMO), and the International Gastric Cancer Association (IGCA). Professor Leong is an active clinician researcher who is involved in both translational research programs as well as clinical research. He is internationally recognised as a leader in the management and research of gastrointestinal cancers.

Summary of presentation

TOPGEAR – A randomized phase 3 trial of perioperative chemotherapy with or without preoperative chemoradiotherapy for resectable gastric cancer; an intergroup trial of AGITG, NHMRC CTC, TROG, EORTC and CCTG.

Globally significant results from the TOPGEAR trial have recently been reported and provide practice-changing evidence about preoperative chemoradiotherapy for gastric and gastro-oesophageal junction cancers. The findings were announced at the European Society for Medical Oncology (ESMO) Congress in Barcelona and published simultaneously in the New England Journal of Medicine, providing a high quality answer to a long-standing question in gastro-oesophageal cancer.